Claudins and Cancer: Promising Proteins for Detection and Diagnosis Claudin family proteins are transmembrane proteins that serve as major cell adhesion molecules of tight junctions. “Tight junctions restrict the flow of ions and aqueous molecules between cells, and their permeability is determined by the profile of claudin expression and arrangement of claudins with other proteins […]
Want to Swap Avidin for Streptavidin? 4Plus Your Results When You Switch There are several advantages when using streptavidin versus an avidin complex (ABC). In contrast to avidin, streptavidin is not glycosylated and is therefore uncharged at neutral pH (6.5 versus 10), reducing nonspecific background staining. Streptavidin also lacks the carbohydrate side chains that may […]
June 29, 2020 – Biocare Medical, a leading provider of innovative, automated immunohistochemistry (IHC) reagents and instrumentation, announces a collaborative partnership with Bethyl Laboratories to develop targeted antibodies for cancer research and oncology diagnostics. Bethyl Laboratories has 45 years of experience in antibody development and has been dedicated to supporting scientific discovery to advanced laboratories […]
June 22, 2020 – Biocare Medical, a leading provider of innovative, automated immunohistochemistry (IHC) reagents, instrumentation and detection systems has been mentioned in a recent early release study by the Centers for Disease Control: Pathology and Pathogensis of SARS-CoV-2 Associated with Fatal Corona Virus Disease. The ongoing pandemic of the novel coronavirus disease (COVID-19), as […]
Thinking of Automating Your IHC Lab? Are you thinking about automating your IHC Lab? Do you want to increase daily throughput and volume of your lab? Do you need to standardize your staining procedures to reduce variability and improve staining quality? Do you need to reduce hands-on time, decrease cost per slide and better utilize […]
Focus on Concentrates for Flexibility in Your Laboratory Working with antibody concentrates can seem intimidating to new users. However, regular users of concentrated antibodies quickly find that they are both easy to use and offer great advantages. While ready-to-use antibody formats come pre-diluted to a set concentration, antibody concentrates can be titered to any desired […]
Last Updated: March 16, 2020, 5:00 PM PST Dear Biocare Customers, Biocare Medical has been closely monitoring developments around the news of the novel coronavirus (COVID-19). Our COVID-19 preparedness is part of a Company-wide business continuity program. The goal of our planning is to enable Biocare to support our customers’ needs with a minimal level […]
February 13, 2020 – Biocare Medical, a leading provider of innovative, automated immunohistochemistry (IHC) reagents and instrumentation, announces the launch of seven novel IVD IHC antibody markers for clinical diagnostics and research applications.The most recent launch focuses on several immuno-oncology markers, critical in aiding early-stage cancer drug developments and patient treatment. Biocare re-developed a major […]
New p16 INK4a [BC42] monoclonal antibody with exceptional sensitivity and specificity San Francisco, CA, September 3, 2019 – Biocare Medical, LLC, a leading provider of innovative, automated immunohistochemistry (IHC) instrumentation and reagents, announces the release of a new mouse monoclonal antibody, p16 INK4a, for in vitro diagnostic (IVD) use in the qualitative identification of the […]
Approximately 12,000 men and women in the United States are diagnosed with gallbladder cancer annually, leading to an annual estimated 4,000 deaths.1 Gallbladder and other biliary cancers are comparatively rare in the United States, with about 0.7% of new cancer cases classified as gallbladder, contributing approximately 0.6% of cancer deaths yearly.1 Worldwide, gallbladder and other […]