A Comparative Study of HIER Methods: Online vs Offline Retrieval The objective of this study is to examine the efficiency and effectiveness of heat induced epitope retrieval (HIER) when performed on a fully automated instrument using single-sided application of a heating element and topical dispense of retrieval buffer solution, commonly referred to as online retrieval, […]
Biocare Medical reagents and antibodies were recently utilized in a study by researchers at Tufts University and published in Nature Medicine, reviewing an experimental SARS-Cov-2 vaccine’s efficacy. Using the Biocare intelliPATH FLX instrument with MACH2 Detection, Background Eraser, and Microglia antibody, researchers tracked viral replication and disease symptoms in hamsters administered high-dose intranasal SARS-CoV-2 infection […]
Biocare Medical, a leading provider of innovative, automated immunohistochemistry (IHC) reagents and instrumentation, announces the launch of three novel IVD IHC antibody markers at the forefront of clinical diagnostic and research applications. These three markers SMAD4 [EP618Y], BAP1, and BCA-225 [Cu-18] may aid pathologists in critical prognostic and diagnostic decisions – impacting patient outcome. Each […]
Which Biocare Antibodies Are Right For Your Roche or Ventana Instrument? Biocare Medical has created a line of prediluted antibodies specially formulated for use on Roche and Ventana platforms. This line of antibodies, called “UltraLine Antibodies”, is optimized utilizing Biocare’s ISO-certified antibody development process on the Roche and Ventana Benchmark Ultra® slide-staining system to ensure […]
August, 4 2020 – Biocare Medical LLC, a leading provider of innovative, automated immunohistochemistry (IHC) reagents and instrumentation, in collaboration with Bethyl Laboratories announces the release of a new rabbit monoclonal antibody, TIGIT [BLR047F] antibody for in vitro diagnostic (IVD) use in the qualitative identification of the TIGIT protein by immunohistochemistry (IHC) in formalin-fixed paraffin-embedded […]
Claudins and Cancer: Promising Proteins for Detection and Diagnosis Claudin family proteins are transmembrane proteins that serve as major cell adhesion molecules of tight junctions. “Tight junctions restrict the flow of ions and aqueous molecules between cells, and their permeability is determined by the profile of claudin expression and arrangement of claudins with other proteins […]
Want to Swap Avidin for Streptavidin? 4Plus Your Results When You Switch There are several advantages when using streptavidin versus an avidin complex (ABC). In contrast to avidin, streptavidin is not glycosylated and is therefore uncharged at neutral pH (6.5 versus 10), reducing nonspecific background staining. Streptavidin also lacks the carbohydrate side chains that may […]
June 29, 2020 – Biocare Medical, a leading provider of innovative, automated immunohistochemistry (IHC) reagents and instrumentation, announces a collaborative partnership with Bethyl Laboratories to develop targeted antibodies for cancer research and oncology diagnostics. Bethyl Laboratories has 45 years of experience in antibody development and has been dedicated to supporting scientific discovery to advanced laboratories […]
June 22, 2020 – Biocare Medical, a leading provider of innovative, automated immunohistochemistry (IHC) reagents, instrumentation and detection systems has been mentioned in a recent early release study by the Centers for Disease Control: Pathology and Pathogensis of SARS-CoV-2 Associated with Fatal Corona Virus Disease. The ongoing pandemic of the novel coronavirus disease (COVID-19), as […]
Thinking of Automating Your IHC Lab? Are you thinking about automating your IHC Lab? Do you want to increase daily throughput and volume of your lab? Do you need to standardize your staining procedures to reduce variability and improve staining quality? Do you need to reduce hands-on time, decrease cost per slide and better utilize […]