Fluorescence in situ hybridization (FISH) probes have become a cornerstone of cytogenetic analysis in hematological malignancies. These targeted probes allow for the detection of specific chromosomal abnormalities associated with various leukemias and myelodysplastic syndromes (MDS). This white paper will explore the importance of FISH probes for Chronic Lymphocytic Leukemia (CLL) and Myelodysplastic Syndromes (MDS)

Nucleic acid probes are invaluable tools in molecular biology, enabling clinical laboratories and researchers to detect specific DNA or RNA sequences within a sample. In this white paper, we explore the key differences between three prominent probe types: DNA probes, RNA probes, and cDNA probes. We delve into their what they are, how they are […]

The use of a curated selection of antibodies to target protein characteristics of distinct cell lineages has been in practice in clinical laboratories for many years. The ability for pathologists to identify cells of unknown origin via the use of Immunohistochemistry (IHC) is extremely important to aid in the diagnosis, treatment, and prognosis for their […]

Buffalo, New York – April 1, 2024 – Empire Genomics Corp has been awarded a national group purchasing agreement for Molecular Analyzers, Reagents with Premier, Inc. Effective 02/01/2024, the new agreement allows Premier members, at their discretion, to take advantage of special pricing and terms pre-negotiated by Premier for FISH (Fluorescent in situ Hybridization) Probes. […]

Cluster of Differentiation 54 (CD54), also known as Intercellular Adhesion Molecule 1 (ICAM-1), is a 90 kDa glycosylated transmembrane protein of the immunoglobulin superfamily. CD54 (ICAM-1) can play an important role in immunological synapse formation, T-cell activation, leukocyte migration, and numerous cellular immune responses.1 CD54 (ICAM-1) also interacts with integrin receptors on leukocytes, such as […]

[San Francisco, California, January 4, 2024] – Biocare Medical, a leader in fully open automated instrumentation, announces a collaboration with Molecular Instruments® (MI), the inventor of the HCR™ Imaging technology. This partnership brings together Biocare Medical’s expertise in automated bioimaging systems with MI’s suite of advanced HCR™ Products, setting a new standard in automated in […]

The 5′ and 3′ ends of DNA are fundamental to its structure and function, particularly in the process of DNA replication. These structural ends are also significant in a variety of molecular biology techniques, including Fluorescence in Situ Hybridization (FISH), a clinical testing method used to detect and study genetic abnormalities.

November 30, 2023* – Biocare Medical, a leader in immunohistochemistry (IHC) and in situ hybridization (ISH) diagnostics, is proud to introduce the intelliPATH+ Advanced Staining Instrument. This state-of-the-art upgrade solidifies Biocare Medical’s dedication to superior automated IHC staining processes and marks a significant expansion of its advanced, automated staining portfolio, which includes the acclaimed ONCORE […]

Mesothelioma is a rare but aggressive cancer affecting the mesothelial lining of the lungs, abdomen, reproductive system, or heart. It is often challenging to diagnose due to its similarities to other conditions. Immunohistochemistry (IHC) staining can play a crucial role in the accurate diagnosis and subtyping of mesothelioma.

About Biocare Medical Biocare Medical is a global leader in solutions for cancer research and diagnostics, providing world-class reagents, including tissue-conserving simultaneous Multiplex IHC antibody cocktails and detections; renowned Customer Care; and a comprehensive suite of advanced instrumentation for IHC, molecular, and histology testing. Customers include clinical anatomic pathology laboratories, pharmaceutical companies, CROs, and biotechnology […]