Biocare Medical is proud to announce the launch of RISH™

A new, innovative, chromogenic ISH technology: reducing protocol length from two days to approximately 2.5 hours. In a simplified protocol we have removed the need for RNase free solutions & labware, the overnight hybridization and harsh stringent wash conditions. The proprietary DNA probe technology ensures high specificity and accuracy for the target. The result is […]

ONCORE Pro’s Dual Small Footprint Offers a Solution to the Race for Space in IHC Laboratories

A reality of the medical industry today is that space is at a premium. Whether it is in a hospital environment or independent practice, medical laboratories face space constraints. Immunohistochemistry (IHC) laboratories have dealt with this squeeze by optimizing workflow and carefully managing their inventory. However, storage areas may remain scarce and over-utilized despite their […]

An Overview of Biocare Medical’s Instruments for Immunohistochemistry and In Situ Hybridization Procedures

As a leader in the fields of immunohistochemistry (IHC) and in situ hybridization (ISH), Biocare Medical has, for more than 20 years, offered a variety of instruments used in these staining procedures. Biocare has instruments that can meet your need for high-quality staining at a reasonable cost, whether your lab regularly performs a high volume […]

Buff Up on Buffers and Surfactants

Wash buffers are an integral part of immunohistochemical (IHC) procedures. They are used after each incubation step to wash away excess reagent from the specimen and maintain a constant pH by “soaking up” any free hydrogen (H+) ions. This feature helps maintain the morphological characteristics of antibodies and their epitopes, which enables specific binding. The […]

Biocare Basics: Optimization

Proper optimization is vital for successful immunohistochemical (IHC) testing. An optimal IHC protocol can be characterized by its ability to consistently and unambiguously determine how the antigen is expressed in the tissue. Optimization is fundamental to reducing the risk of both false positive and false negative results.1 The protocol must be able to identify both […]

Alternatives to Lysol for Cleaning Automated Instrumentation

Regular cleaning is an essential part of instrument maintenance, but what happens if you don’t have Lysol? Following recommended cleaning procedures to remove residues and sterilize instrument components will improve instrument performance and help extend the instrument’s lifespan. This white paper looks at Lysol alternatives for cleaning to ensure your automation platform keeps running perfectly! […]

Biocare Basics: Validation

Validation is an essential step for setting up a new laboratory procedure, whether it incorporates immunohistochemical (IHC) or routine ematoxylin and eosin (H&E) staining. The validation process involves repeatedly testing the procedure over a large quantity and range of specimens in order to ensure the procedure will yield consistent and reproducible results. This, in turn, […]

The Benefits of Using Tissue Microarrays (TMAs) In Your Lab

Tissue microarrays (TMAs) are paraffin blocks that include multiple samples from different tissue types meant to provide a comprehensive multiplex staining profile. The sections from TMA blocks can be used for all types of tissue staining techniques, including immunohistochemistry and in situ hybridization.  In order to create a TMA block, cylindrical tissue samples are collected […]

Performing IHC Staining Procedures in the Mohs Surgery Lab: Why the ‘Kit’ Approach May Not Be the Best Approach

Mohs IHC Staining Procedures: Why the ‘Kit’ Approach May Not Be the Best Mohs surgery is a quick and highly effective procedure designed to treat skin cancer. This surgical procedure can be used to treat basal cell carcinoma, squamous cell carcinoma, and melanoma and has success rates as high as 99 percent.1 During a Mohs […]

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