Fully Open IHC & FISH Automation
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IHC, ISH, IF & FISH

Utilize Biocare reagents or Third Party Reagents

Simultaneous Multiplex IHC capabilities

Hazardous Waste Separation

Simple Design, Simple Software

Conserve Reagent with 130uL Dispense Volume

Compact System with Minimal Bulk Containers

Unlock Your Research Potential The ONCORE PRO X is a fully open slide staining system that simplifies and automates staining procedures used in Immunohistochemistry (IHC), Fluorescence In Situ Hybridization (FISH) and In Situ Hybridization (ISH). Biocare Medical offers advanced ready-to-use reagents for the research slide stainer. Alternatively, you can use third-party probes for your laboratory research.

The fully open slide stainer provides flexibility and precision, allowing researchers to optimize the staining process for more accurate and detailed results. ONCORE Pro X processes 1 to 36 microscope slides in each staining run and allows each slide to operate at different protocols, resulting in a high throughput. The instrument also enables customization of agitation frequency, incubation time and temperatures, which is ideal for maximizing staining intensity.

Using the ONCORE Pro X slide stainer for research takes away time-consuming hands-on intervention, enhancing workflows and improving efficiency.

  • Open, Flexible Platform for Research & Development
  • Automate Third-party Antibodies & Research Probes
  • Pre-optimized Human & Animal Detection for Research
  • Run Independent Protocols in Each Slide Position

Pro Performance For Your Laboratory 
ONCORE Pro X widens your research laboratory’s possibilities by performing
IHC and ISH (both FISH and CISH) in one benchtop platform.

Download Protocols

ONCORE Pro X staining of Molecular Instruments PPIB HCR ISH in Warp Red chromogen, CD3 IHC in Vina Green chromogen. Image courtesy of Ensigna Biosystems

ONCORE Pro X staining of Akoya TSA panel (CD4 – Green, CD8 – Yellow, CD68 – Orange, FoxP3 – Red, DAPI Counterstain). Image courtesy of Ensigna Biosystems

ONCORE Pro X combined detection of Her2 Protein (IF – Red), ERBB2/Copy Control 17 FISH – Green/Orange, and ERBB2 mRNA ISH (Cyan).

System specifications

Classification

RUO

Slide Capacity

36 slides

Reagent Rack

One reagent rack holds a maximum of 40 reagent vials

Antigen Retrieval Temperature Range

Room temperature to 103°C; Max 110°C at Sea Level

Multi-Dispensing Syringe Capacity

5mL

Dispense Volume

Antibody: 140uL; Reagent: 65 minimum – 400 μl maximum

DePar Dispense Volume

DS1 – 260uL and DS2 – 215uL

Carboys & Waste

Wash Buffer (2L), Hazardous (4L) and Non-Hazardous Waste (4L)

Unit Control

One Instrument Per Computer

Instrument Weight

125lbs (57 kgs)

Instrument Dimensions

36.5 in x 22 in x 24 in / 93 cm x 56 cm x 61 cm (Door Closed)

36.5 in x 36 in x 24 in / 93 cm x 91 cm x 61 cm (Door Open)

Electrical Requirements

120V 110/120V (±10%) 60Hz (±2Hz) 850 watts

220V 220/240V (±10%) 50Hz (±2Hz) 850 watts

Voltage Tolerance

100 to 240 AC

Noise Rating

Minimum Operating Noise 47.0 dBA, Maximum Operating Noise 69.6 dBA

Reports

Slide Barcode, Slide Information, Staining Runs

Ultimate Flexibility Meets Advanced Productivity

Complete Automation
ONCORE Pro X Automated Slide Staining System is a compact and convenient bench-top instrument that can perform immunohistochemistry (IHC) and in-situ hybridization (ISH) procedures on formalin-fixed paraffin-embedded (FFPE) tissues. The on-board capabilities include slide baking, deparaffinization, antigen retrieval, counterstaining, and antibody or probe detection for IHC, Multiplex IHC and ISH applications.
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Convenient & Easy to Use
ONCORE Pro X contains multiple features for added convenience, flexibility, and ease of use. The system’s software interface is intuitive and easy to use, requiring minimal user interaction from the beginning-to-end of a run. ONCORE Pro X also utilizes 2-D Matrix labels that can be printed for patient slides, significantly reducing patient identification errors. Independent slide positions allow for unique protocols to be performed on individual slides during a run.

Innovative Technologies
ONCORE Pro X utilizes unique reaction modules that protect slides between a heated platform and a reagent containment chamber. These chambers provide gentle agitation during reagent incubation to maximize stain intensity. Reagent vials are identified using RFID technology which stores vital information including name, lot number, expiration date, and the number of tests minimizing user error through real-time tracking of reagent volumes.

Learn More About ONCORE Pro