Fully Automated Slide Stainer
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Complete Benchtop IHC & ISH Automation

Fully Automated IHC/ISH/FISH Staining

Optimized, Ready-To-Use reagents

Hazardous Waste Separation

Simple Design, Simple Software

Conserve Reagent with 130uL Dispense Volume

Compact System with Minimal Bulk Containers

Pro Performance For Your Laboratory

The ONCORE PRO® Automated Slide Staining System now performs fully automated ISH so you can run your FISH probes and CISH probes with full automation and the convenience of a compact bench-top system.

The in vitro diagnostic (IVD) labeled the ONCORE Pro Automated Slide Staining System a compact powerhouse for any clinical laboratory. ONCORE Pro opens a world of possibilities to perform IHC, ISH, FISH, and CISH in a single compact benchtop platform. The ONCORE Pro processes up to 36 slides in a single run, with the ability to perform independent protocols at each slide position for high-throughput slide processing.


This stainer machine’s slide processing is facilitated by unique reaction modules that enclose slides between a heated platform and a novel reagent containment chamber. Reagents are dispensed onto slides through a port attached to each chamber, allowing for minimal reagent usage and waste production. These unique chambers provide gentle agitation to enhance incubation throughout the staining procedure, maximizing staining intensity while minimizing background. The ONCORE Pro also accommodates simultaneous Multiplex IHC, allowing fast and efficient processing of multiple IHC markers on a single slide.

ONCORE Pro fully automates the staining process utilizing advanced online antigen retrieval technology, pre-optimized reagents, and ready to use antibodies to enhance laboratory workflow, increase laboratory efficiency, and reduce hands-on processing time. Solve modern-day challenges facing your laboratory now and in the future with the advanced automated slide staining machine, ONCORE Pro.

  • Fully Automated Online Antigen Retrieval (HIER)
  • Ready to Use Single and Multiplex IHC Staining Protocols
  • Conserve Bench Space with Compact Footprint
  • Intuitive Software for Ease of Use & Protocol Programming
  • 2-D Matrix Labels Virtually Eliminate Patient ID Errors
  • Waste Separation Reduces Hazardous Waste & Disposal Costs

High-Throughput Capacity, Random Access Automation
ONCORE Pro benchtop platform expands the possibilities of your laboratory by performing IHC and ISH (FISH and CISH).

Download Protocols

Ultimate Flexibility Meets Advanced Productivity

Complete Automation
ONCORE Pro X Automated Slide Staining System is a compact and convenient bench-top instrument that can perform immunohistochemistry (IHC) and in-situ hybridization (ISH) procedures on formalin-fixed paraffin-embedded (FFPE) tissues. The on-board capabilities include slide baking, deparaffinization, antigen retrieval, counterstaining, and antibody or probe detection for IHC, Multiplex IHC and ISH applications.

Convenient & Easy to Use
ONCORE Pro X contains multiple features for added convenience, flexibility, and ease of use. The system’s software interface is intuitive and easy to use, requiring minimal user interaction from the beginning-to-end of a run. ONCORE Pro X also utilizes 2-D Matrix labels that can be printed for patient slides, significantly reducing patient identification errors. Independent slide positions allow for unique protocols to be performed on individual slides during a run.

Innovative Technologies
ONCORE Pro X utilizes unique reaction modules that protect slides between a heated platform and a reagent containment chamber. These chambers provide gentle agitation during reagent incubation to maximize stain intensity. Reagent vials are identified using RFID technology which stores vital information including name, lot number, expiration date, and the number of tests minimizing user error through real-time tracking of reagent volumes.

Ready to Use Reagents
IHC reagents and antibodies specifically designed for ONCORE Pro provide exceptional staining quality as well as the ability to use primary antibodies from alternate vendors. ONCORE Pro antibody menu is built to serve a wide variety of laboratories and tissue types, making it an ideal solution for clinical applications. Multiplex IHC capability and Multiplex detections for the ONCORE Pro conserves patient tissue, reduces slide volume, and can lower labor costs by 50%.

System specifications

Slide Capacity

36 slides

Reagent Rack

One reagent rack holds a maximum of 40 reagent vials

Antigen Retrieval Temperature Range

Room temperature to 103°C; Max 110°C at Sea Level

Multi-Dispensing Syringe Capacity


Dispense Volume

Antibody: 130uL; Reagent: 65 minimum – 400 μl maximum

DePar Dispense Volume

DS1 – 240uL and DS2 – 200uL

Carboys & Waste

Wash Buffer (2L), Hazardous (4L) and Non-Hazardous Waste (4L)

Unit Control

One Instrument Per Computer

Instrument Weight

125lbs (57 kgs)

Instrument Dimensions

36.5 in x 22 in x 24 in / 93 cm x 56 cm x 61 cm (Door Closed)

36.5 in x 36 in x 24 in / 93 cm x 91 cm x 61 cm (Door Open)

Electrical Requirements

120V 110/120V (±10%) 60Hz (±2Hz) 850 watts

220V 220/240V (±10%) 50Hz (±2Hz) 850 watts

Voltage Tolerance

100 to 240 AC

Noise Rating

Minimum Operating Noise 47.0 dBA, Maximum Operating Noise 69.6 dBA


Slide Barcode, Patient Information, Staining Runs


HL7 Server Connection and MSSQL Database Connection

Learn More About ONCORE Pro