HPV Cocktail Broad Spectrum

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The HPV Broad Spectrum antibody was produced against SDS-disrupted bovine papillomavirus type 1 (BPV-1) and was used to identify its product of the L1 open reading frame. IH8 was found to be reactive with purified major capsid protein (MCP). The antibody was tested with ELISA and an immunofluorescent technique. It detected HPV-1, 6, 11, 16, 18 and 31 in formalin-fixed, paraffin-embedded (FFPE) biopsy specimens. The CAMVIR-1 antibody reacted with a protein in cells infected with L1-vaccinia virus and the protein was present in HPV16. Other HPV isotypes may also be reactive with the Broad Spectrum HPV antibody, but have not been tested.

Intended Use

RUO

Species Reactivity

Human

Source

Mouse Monoclonal

Clone

BPV-1/1H8 + CAMVIR-1

Isotype

IgG + IgG2a

Antigen

HPV Cocktail Broad Spectrum (HPV-1, 6, 11, 16-16, 18 and 31)

Localization

Nuclear

Positive Control

Infected cervical biopsy

Download OUS Datasheet

Legal Notice

IVD is NOT for Sale in the United States but may be available in certain countries outside of the United States, please contact your local distributor for more information.

1. Cowsert LM, Pilacinski WP, Jenson AB. Identification of the bovine papillomavirus L1 gene product using monoclonal antibodies. Virology 1988 Aug;165(2):613
2. Center for Disease Control Manual. Guide: Safety Management, NO. CDC-22, Atlanta, GA. April 30, 1976 “Decontamination of Laboratory Sink Drains to Remove Azide Salts.”
3. National Committee for Clinical Laboratory Standards(NCCLS). Protection of laboratory workers from infectious diseases transmitted by blood and tissue; proposed guideline. Villanova, PA 1991;7(9). Order code M29-P.

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