The CAMVIR-1 antibody was raised against the major capsid protein L1 of human papillomavirus HPV-16 antibody, using a recombinant vaccinia virus that expresses the L1 protein. This antibody also detects the HPV-16 L1 antigen in formalin-fixed, paraffin embedded biopsy specimens and on routine cervical smears. The antibody reacts strongly and consistently with specimens containing HPV-16 or HPV-33, but very weak reactions were occasionally observed with biopsy specimens or smears containing HPV-6 or HPV-11.
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