Estrogen Receptor (ER) [6F11]

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The estrogen receptor mouse antibody (ER) is a 66-kDa protein that mediates the actions of estrogens in estrogen-responsive tissues. The ER gene consists of more than 140kb of genomic DNA divided into 8 exons. These translate into a protein with six functionally discrete domains, labeled A through F. This antibody can be use for labeling estrogen targeted tissues such as breast.

Intended Use

ASR

Species Reactivity

Human, Mouse, Rat

Source

Mouse Monoclonal

Clone

6F11

Isotype

IgG1/kappa

Antigen

ER protein

Localization

Nuclear

Positive Control

Breast Carcinoma

Download OUS Datasheet

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1. Bevitt DJ et al. New monoclonal antibodies to oestrogen and progesterone receptors effective for paraffin section immunohistochemistry. J Pathol 1997 Oct; 183(2):228-32.
2. Center for Disease Control Manual. Guide: Safety Management, NO. CDC-22, Atlanta, GA. April 30, 1976 “Decontamination of Laboratory Sink Drains to Remove Azide Salts.”
3. National Committee for Clinical Laboratory Standards (NCCLS). Protection of laboratory workers from infectious diseases transmitted by blood and tissue; proposed guideline. Villanova, PA 1991; 7(9). Order code M29-P.

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