Product Description
The p63 + CK5 Multiplex IHC stain has been especially designed for squamous cell carcinomas, particularly those derived in lung cancer. p63, a homolog of the tumor suppressor p53, has been identified in basal cells in the epithelial layers of a variety of tissues, including epidermis, cervix, urothelium, breast and prostate.15 CK5 is a 58 kDa protein that is closely related to CK6.16 CK5 tissue distribution is in many non-keratinizing stratified squamous epithelia such as tongue mucosa, basal epithelia hair follicles, trachea, as well as basal cells in prostate glands and myoepithelial cells in mammary glands.16
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