Amyloidosis is a heterogeneous group of disorders characterized by extracellular deposition of abnormal protein fibrils, which are derived from different proteins. Amyloid P antibody reacts with amyloid deposits in all tissues including kidney, rectum and brain. The application of Congo Red, Amyloid P antibody and Amyloid A antibody in tissues with amyloid deposits has been shown to be superior to Congo Red and other histochemical stains. Small and minute amounts of amyloid can be detected with both Amyloid P and Amyloid A antibodies and thus could aid in allowing earlier treatment before organ damage has occurred.
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