Estrogen Receptor (ER) [1D5]

Clear
SKU: 054 Categories: ,
Related Products

The estrogen receptor antibody (ER) is a 66 kDa protein that acts as an estrogen-dependent, nuclear hormone receptor. Studies have shown ER is present in the nuclei of epithelial cells in normal breast and endometrial tissues, as well as a subset of breast carcinomas. The ER protein has six functionally discrete domains; labeled A through F. ER [1D5] reacts with the amino-terminal domain in the A/B region of ER-alpha. This clone has been established to work in formalin-fixed, paraffin-embedded tissues and has been published in numerous breast cancer research studies.

Intended Use

ASR

Species Reactivity

Human

Source

Mouse Monoclonal

Clone

1D5

Isotype

IgG1 /kappa

Antigen

ER protein

Localization

Nuclear

Positive Control

Breast Carcinoma

Download OUS Datasheet

Legal Notice

IVD is NOT for Sale in the United States but may be available in certain countries outside of the United States, please contact your local distributor for more information.

1. Paech K, et al. Differential ligand activation of estrogen receptors ERalpha and ERbeta at AP1 sites. Science 97. Sept 5; 277(5331):1508-1510.
2. Center for Disease Control Manual. Guide: Safety Management, NO. CDC-22, Atlanta, GA. April 30, 1976 “Decontamination of Laboratory Sink Drains to Remove Azide Salts.”
3. National Committee for Clinical Laboratory Standards (NCCLS). Protection of laboratory workers from infectious diseases transmitted by blood and tissue; proposed guideline. Villanova, PA 1991; 7(9). Order code M29-P.

Reviews


There are no reviews yet.

Be the first to review “Estrogen Receptor (ER) [1D5]”