CD43

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CD43 antibody recognizes a 95/115/135kDa (depending upon the extent of glycosylation) cell surface glycoprotein, identified as CD43 (leukosialin, sialophorin, or leukocyte sialoglycoprotein) CD43 is shown to be expressed on all thymocytes, T-cells and in endothelial cells. CD43 may also aid in distinguishing extranodal marginal zone B-cell lymphoma from other reactive processes in the skin. The CD43 antibody has also been shown to be useful in aiding in the identification and classification of T-cell malignancies and low-grade B-cell lymphomas.

Intended Use

IVD

Species Reactivity

Human

Source

Mouse Monoclonal

Clone

DF-T1

Isotype

IgG1

Antigen

CD43

Localization

Cell surface

Positive Control

Tonsil or T-cell lymphoma

1.Tomaszewski MM, Abbondanzo SL, Lupton GP. Am J Dermatopathol. 2000 Jun; 22(3):205-11.
2.Muretto P. European J Histochem. 1995; 39(4):301-8
3. de Smet W, Walter H, van Hove L.. Immunology. 1993 May; 79(1):46-54.6.Kaufmann O, et al. Am J Clin Pathol 1997 Dec; 108(6):669-73.

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