CD19

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CD19 antibody recognizes a 95kD cell surface glycoprotein, which is expressed by cells of B-cell lineage and follicular dendritic cells. CD19 is an important signal transduction molecule in the regulation of B-lymphocyte development, activation and differentiation. Studies have shown that CD19 is absent in plasma cells, most T-cell lymphomas and in lymphocyte predominant Hodgkin’s. It has been observed in lymphomas and leukemias but often weak/negative in follicular lymphoma or diffuse large B-cell lymphoma. CD19 may provide useful diagnostic information for the study of B-lymphoproliferative disorders.

Intended Use

IVD

Species Reactivity

Human

Source

Mouse Monoclonal

Clone

CD19

Isotype

IgG1

Antigen

CD19

Localization

Cytoplasmic/membrane

Positive Control

Tonsil

Download Data Sheet
Download RUO Data Sheet
Download SDS Sheet

Regulatory Notice: Biocare’s IVD-labeled products comply with US-FDA and European IVDD regulation. Other regions may have additional requirements for such labeling, please contact your local distributor.

1. Masir N, et al. Histopathology. 2006 Feb; 48(3):239-46.
2. Ferkolj I, Ihan A, Markovic S. Hepatogastroenterology. 2005 Jul-Aug; 52(64):1128-33.
3. Ginaldi L, et al. J Clin Pathol. 1998 May; 51(5):364-9.

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