Biotinylated Bromodeoxyuridine Antibody recognizes bromodeoxyuridine (BrdU), an analog to thymidine and can be incorporated into replicating DNA during the S-phase of the cell cycle. The BrdU antibody can be used for DNA labeling index, evaluation of DNA synthesis and cell proliferation studies. This antibody is biotinylated and thus eliminates the need for a biotinylated secondary antibody. This antibody can be used in all species, including mouse and rat tissues.
1. McGinley JN, Knott KK, Thompson HJ. Effect of Fixation and Epitope Retrieval on BrdU Indices in Mammary Carcinomas. J Histochem Cytochem 2000 Mar;48 (3):355-362.
2. Tacha DE, Bowman PE, McKinney L. High Resolution Light Microscopy and Immunocytochemistry Using Glycol Methacrylate-Embedded Sections and ImmunoGold-Silver Staining. J of Histochemistry; June, 1993.
3. Center for Disease Control Manual. Guide: Safety Management, NO. CDC-22, Atlanta, GA. April 30, 1976 “Decontamination of Laboratory Sink Drains to Remove Azide Salts.”
4. Clinical and Laboratory Standards Institute (CLSI). Protection of Laboratory workers from occupationally Acquired Infections; Approved guideline-Third Edition CLSI document M29-A3 Wayne, PA 2005.