Tumor Associated Glycoprotein antibody [B72.3], also known as TAG-72, has the properties of a mucin. The majority of human adenocarcinomas including colorectal, pancreatic, gastric, ovarian, endometrial, mammary and non-small cell lung cancer display some cell populations that are positive for TAG-72 staining. Weak or no reactivity has been observed with most cell types of normal adult tissue with the exception of the secretory endometrium. Tumor Associated Glycoprotein [B72.3] is reportedly useful in distinguishing pulmonary adenocarcinomas from pleural mesotheliomas.
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