Hepatocyte Specific Antigen

Product Description

Hepatocyte Specific Antigen (HSA) is considered specific for normal and neoplastic hepatocytes.¹⁵ Expression has been demonstrated consistently in the majority of hepatocellular carcinomas.^15,17,18 Studies have shown HSA can be used in a panel with Glypican-3, CEA, CK7, AFP and CD10.^16,18

Specifications

1. Maitra A, Murakata LA, Albores-Saavedra J. Immunoreactivity for hepatocyte paraffin 1 antibody in hepatoid adenocarcinomas of the gastrointestinal tract. Am J Clin Pathol. 2001 May;115(5):689-94.
2. S-Y Xiao, et al. CD10/CALLA expression in Hepatocellular carcinoma: A useful Marker for Differential Diagnosis. Abstract 1209, United States and Canadian Academy of Pathology Annual Meeting; March 2001.
3. Fasano M, et al. Immunohistochemical evaluation of hepatoblastomas with use of the hepatocyte-specific marker, hepatocyte paraffin 1, and polyclonal CEA. Mod Pathol. 1998 Oct;11(10):934-8.
4. Leong AS, et al. Hep Par 1 and selected antibodies in the immunohistological distinction of hepatocellular carcinoma from cholangio-carcinoma, combined tumours and metastatic carcinoma. Histopathology. 1998 Oct;33(4):318-24.
5. Center for Disease Control Manual. Guide: Safety Management, NO. CDC-22, Atlanta, GA. April 30, 1976 “Decontamination of Laboratory Sink Drains to Remove Azide Salts.”
6. Clinical and Laboratory Standards Institute (CLSI). Protection of Laboratory workers from occupationally Acquired Infections; Approved guideline-Third Edition CLSI document M29-A3 Wayne, PA 2005.