CD44
$295.00 – $377.00
Description
Product Description
CD44 is a transmembranous glycoprotein (80 kDa) responsible for cell adhesion that is expressed in a wide range of normal tissues, such as tonsil, breast, prostate, skin, bladder and cervical squamous epithelium.15 Studies have shown that CD44, also known as HCAM, plays an important role in the cascade of metastasis and progression of human malignant tumors.16 In breast cancer studies, evaluation of CD44 expression has been useful in the differentiation of benign and malignant papillary lesions.16 CD44, as part of a panel that includes CK20, p53, and AMACR, has been shown to be useful in differentiating urothelial carcinoma in situ from normal urothelium or reactive urothelial atypia.17,18 The CD44 predilute (PM380) has been titered specifically for use in bladder cancer.
Specifications
Specifications
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Datasheets & SDS
| Download CE Marked IVD Datasheet |
| Download IVD Datasheet Without CE Mark |
| Download RUO Datasheet |
| Download SDS Sheet |
Browse more documents for this product (IFUs, datasheets, translations, SDS, and more).
References
1. Balic M, et al. Clin Cancer Res. 2006 Oct; 12(19):5615-21.
2. Diaz LK, et al. Clin Cancer Res. 2005 May; 11(9):3309-14.
3. Tse GM, et al. J Clin Path. 2005 Nov; 58(11):1185-8.
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