PTEN (Tumor Suppressor)
Price range: $544.00 through $3,133.00
Description
Product Description
Studies have shown PTEN gene is a tumor suppressor gene that maps to chromosome 10q23. PTEN, a novel tumor suppressor, functions as a regulator of both cell cycle progression and apoptosis.15-16 Potentially, mutation and deletion of PTEN gene may result in a new signal transduction pathway related to human malignant tumors. Studies have demonstrated a reduction of PTEN expression in advanced breast cancers.15
Specifications
Specifications
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Datasheets & SDS
| Download IVD CE Datasheet |
| Download IVD Datasheet |
| Download RUO Datasheet |
| SDS Sheet |
Browse more documents for this product (IFUs, datasheets, translations, SDS, and more).
References
1. Bose S, et al. Reduced expression of PTEN correlates with breast cancer progression. Hum Pathol. 2002 Apr; 33(4):405-9.
2. Bose S, et al. The Akt pathway in human breast cancer: a tissuearray- based analysis. Mod Pathol. 2006 Feb;19(2):238-45.
3. Center for Disease Control Manual. Guide: Safety Management, NO. CDC-22, Atlanta, GA. April 30, 1976 “Decontamination of Laboratory Sink Drains to Remove Azide Salts.”
4. Clinical and Laboratory Standards Institute (CLSI). Protection of Laboratory Workers from Occupationally Acquired Infections; Approved Guideline-Fourth Edition CLSI document M29-A4 Wayne, PA 2014.
