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DepART Solution is a water-soluble deparaffinization reagent that can be used for immunohistochemistry (IHC) and H&E. Unlike other commercially available watersoluble reagents, paraffin is completely removed by this non-flammable solution. DepART Solution eliminates the use of xylenes and alcohols. DepART Solution can be used as part of a two-step deparaffinization retrieval protocol with most retrieval solutions, including Biocare’s Reveal, Diva or Borg. Biocare Medical has performed in-house studies comparing DepART Solution with xylene/alcohol reagents and found equivalent staining results for both IHC and H&E. The DepART Solution can be reused up to 10 times, for a total of 100-200 slides over a period of up to two weeks. Store solution covered, at room temperature between runs.