For decades, the rich brown stain produced by DAB has made it the chromogen of choice for IHC stains. However, precautions must be taken due to the fact that DAB is a known mutagen and potential carcinogen. Since DAB is considered a hazardous material, disposal of DAB-contaminated waste is subject to environmental, health and safety […]
Antigen retrieval (AR) is a fundamental part of any IHC protocol. However, with so many different names for this one process, it can be difficult to recognize what an individual protocol or paper is referring to. Why is it sometimes called “retrieval” and other times simply “pretreatment?” Is ER the same as AR? What is […]
In the preparation of paraffin sections for staining, fixation and processing go hand in hand. Proper tissue fixation ensures tissue processing will be effective, and a lab’s chosen processing method may also influence their choice of fixative.1 Errors in the processing stage have the potential to seriously affect staining quality. However, because tissue specimens vary […]
investment to accelerate growth amid an increasing market demand for Immunohistochemistry instruments and reagents Management will leverage GHO’s extensive healthcare expertise to accelerate R&D, product launches and international expansion GHO in partnership with existing investor Excellere Partners will continue to support the Biocare Medical team in accelerating strategic growth initiatives LONDON–(BUSINESS WIRE)–Global Healthcare Opportunities, or […]
A reality of the medical industry today is that space is at a premium. Whether it is in a hospital environment or independent practice, medical laboratories face space constraints. Immunohistochemistry (IHC) laboratories have dealt with this squeeze by optimizing workflow and carefully managing their inventory. However, storage areas may remain scarce and over-utilized despite their […]
As a leader in the fields of immunohistochemistry (IHC) and in situ hybridization (ISH), Biocare Medical has, for more than 20 years, offered a variety of instruments used in these staining procedures. Biocare has instruments that can meet your need for high-quality staining at a reasonable cost, whether your lab regularly performs a high volume […]
Wash buffers are an integral part of immunohistochemical (IHC) procedures. They are used after each incubation step to wash away excess reagent from the specimen and maintain a constant pH by “soaking up” any free hydrogen (H+) ions. This feature helps maintain the morphological characteristics of antibodies and their epitopes, which enables specific binding. The […]
Proper optimization is vital for successful immunohistochemical (IHC) testing. An optimal IHC protocol can be characterized by its ability to consistently and unambiguously determine how the antigen is expressed in the tissue. Optimization is fundamental to reducing the risk of both false positive and false negative results.1 The protocol must be able to identify both […]
Biocare Medical has been busy ensuring you supply the highest quality reagents for your laboratory on every automated platform. Have you seen the latest releases from us, such as CD137, PSAP and LMO2? We have increased our menu of antibodies for the Leica Bond* with our Q Series reagents and the Roche BenchMark Ultra with […]
Regular cleaning is an essential part of instrument maintenance, but what happens if you don’t have Lysol? Following recommended cleaning procedures to remove residues and sterilize instrument components will improve instrument performance and help extend the instrument’s lifespan. This white paper looks at Lysol alternatives for cleaning to ensure your automation platform keeps running perfectly! […]