Carcinoembryonic Antigen

Product Description

The CEA gene family belongs to the immunoglobulin gene superfamily (IgSF) and comprises a large number of genes. The cell surface associated CEA proteins are heavily glycosylated, abundantly expressed and multifunctional.^15,16 The CEA (CD66e) COL-1 clone shows no detectable reactivity for other CEA family members such as NCA or BGP. COL-1 is useful in detecting early foci of gastric carcinoma and distinguishing pulmonary adenocarcinomas from mesothelioma. It stains many types of adenocarcinoma but does not stain benign glands, stroma, or malignant prostatic cells. Normal colon, without colon disease, is unreactive, but a weak reactivity was in normal-appearing mucosa several centimeters remote from colon cancer.¹⁷

Specifications

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