CD99
CD99 antigen, a 32 kD T-Cell surface glycoprotein, is also known as MIC2, E2, 12E7, HuLy-m6 or FMC29. This antigen is expressed on the cell membrane of some lymphocytes, cortical thymocytes, and granulosa cells of the ovary. CD99 is also expressed by most pancreatic islet cells, Sertoli cells of the testis and some endothelial cells. Mature granulocytes express limited or no CD99. Engagement of distinct epitopes on CD99 rapidly induces T-cell death by a novel caspase-independent pathway. CD99 is a highly restricted cell surface antigen of Ewing’s sarcoma and primitive peripheral neuroectodermal tumors; therefore, CD99 is a sensitive marker for Ewing’s sarcoma and peripheral neuroectodermal tumors and is useful in the differential diagnosis of small blue cell tumors.
| Ordering Information |
Catalog Number |
Volume |
| Concentrate |
CME 392 |
A, C |
| Predilute |
PME 392 |
AA |
| intelliPATH™ |
IP 392 |
G10 |
| VP Echelon |
N/A |
N/A |
| A / AK = 0.1 ml |
B / BK = 0.5 ml |
C / CK = 1.0 ml |
G5 = 5.0 ml |
AA = 6.0 ml |
H / G25 = 25 ml |
L = 100 ml |
