CK7

Breast cancer stained with CK7 antibody

Cytokeratin 7 is an intermediate filament protein (IFP) of 54kDa that recognizes the simple epithelium found in most glandular and transitional epithelia; but not that which is found in the stratified squamous epithelia. This rabbit monoclonal antibody [clone BC1] is highly specific to cytokeratin 7 and shows no cross-reaction with other IFPs. Cytokeratin 7 is expressed in epithelial cells of ovary, lung and breast. It is often used in conjunction with cytokeratin 20 and CDX-2 in distinguishing pulmonary, ovarian and breast carcinomas (CK7+) from most colon carcinomas (CK7-).

Specifications  
Intended Use
Source
Species Reactivity
Clone
Isotype
Antigen
Cellular Localization
Positive Control , ,
Normal Tissue ,
Abnormal Tissue , ,
Ordering Information Catalog Number Volume
Concentrate CRM 339 A, C
Predilute PRM 339 AA
intelliPATH™ IP 339 G10
VP Echelon N/A N/A
A / AK = 0.1 ml B / BK = 0.5 ml C / CK = 1.0 ml G5 = 5.0 ml AA = 6.0 ml H / G25 = 25 ml L = 100 ml