Spirochete (Treponema pallidum) is the causative agent of syphilis. Spirochete can now be successfully localized with a treponema pallidum antibody using immunohistochemical techniques in formalin-fixed, paraffin-embedded (FFPE) tissue. In the past, localization of the spirochete agent was achieved with silver stains such as Steiner’s and/or Warthin-Starry. The spirochete antibody consists of a rabbit purified IgG fraction that is highly specific. Treponema pallidum antibody also cross-reacts with burgdorferi (Lyme disease).
|Download OUS Datasheet|
IVD is NOT for Sale in the United States but may be available in certain countries outside of the United States, please contact your local distributor for more information.
1. Hoang MP, High WA, Molberg KH. Secondary syphilis: a histologic and immunohistochemical evaluation. J Cutan Pathol. 2004 Oct;31(9):595-9.
2. Center for Disease Control Manual. Guide: Safety Management, NO. CDC-22, Atlanta, GA. April 30, 1976 “Decontamination of Laboratory Sink Drains to Remove Azide Salts.”
3. Clinical and Laboratory Standards Institute (CLSI). Protection of Laboratory workers from occupationally Acquired Infections; Approved guideline-Third Edition CLSI document M29-A3 Wayne, PA 2005.