TP53 (17p13) Red + Copy Control 17 Aqua

Product Description

TP53 is the gene which encodes for the p53 tumor suppressor protein. TP53 is activated in many forms of cellular stress including carcinogenesis and exerts multiple anti-proliferative functions1. TP53mutations are one of the most common findings in many human cancers and has been proposed as an effective measure of prognosis2.

Typically the presence of a specific mutation has been correlated with a shorter survival or poor response to treatment. Multiple breast cancer studies have all shown that there was a clear association between mutation and bad prognosis3.

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