TIA-1

Product Description

TIA-1 (T-cell intracytoplasmic antigen) monoclonal antibody reacts with a 15 kDa isoform of a cytoplasmic granule-associated protein that is expressed in cytolytic lymphocytes.^15,16 Expression of the TIA-1 is characteristic of cytotoxic cells regardless of their activation status.¹⁷

Specifications

Regulatory Notice: Biocare’s IVD-labeled products comply with US-FDA and European IVDD regulation. Other regions may have additional requirements for such labeling, please contact your local distributor.

1. Dukers DF et al. A cytotoxic phenotype does not predict clinical outcome in anaplastic large cell lymphomas. J Clin Pathol 1999 Feb;52(2):129-36.
2. Kanavaros P et al. Cytotoxic protein expression in non-Hodgkin’s lymphomas and Hodgkin’s disease. Anticancer Res 1999 Mar-Apr;19(2A):1209-16.
3. Center for Disease Control Manual. Guide: Safety Management, NO. CDC-22, Atlanta, GA. April 30, 1976 “Decontamination of Laboratory Sink Drains to Remove Azide Salts.”
4. National Committee for Clinical Laboratory Standards (NCCLS). Protection of laboratory workers from infectious diseases transmitted by blood and tissue; proposed guideline. Villanova, PA 1991;7(9). Order code M29-P.