p53 Tumor Suppressor Protein

Product Description

p53 Tumor Suppressor Protein (M) [DO-7] recognizes a 53 kDa phosphoprotein identified as the p53 suppressor gene product. It reacts with both mutant and wild type p53. Its epitope maps within the N-terminus (aa 37-45) of p53. p53 acts both as a tumor-suppressor and transcription factor. Activation by DNA damage or other stress signals triggers cell-cycle arrest, apoptosis and DNA repair.^15-16

Specifications

Regulatory Notice: Biocare’s IVD-labeled products comply with US-FDA and European IVDD regulation. Other regions may have additional requirements for such labeling, please contact your local distributor.

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