p40 (M) [BC28]

Product Description

The mouse monoclonal antibody p40 [clone BC28] recognizes an epitope unique to the p40 protein. p40 is selectively expressed in lung SCC, offering an opportunity for improved specificity, resulting in diminished reactivity in lung ADC and increased specificity.¹⁵ Studies have supported the routine use of p40 as an alternative for p63.^15-18

Specifications

1. Bishop JA, Teruya-Feldstein J, Westra WH, Pelosi G, Travis WD, Rekhtman N. Mod Pathol. 2012 Mar;25(3):405-15.
2. Nonaka D. Am J Surg Pathol. 2012 Jun;36(6):895-9.
3. Pelosi G, Fabbri A, Bianchi F, Maisonneuve P, Rossi G, Barbareschi M, Graziano P, Cavazza A, Rekhtman N, Pastorino U, Scanagatta P, Papotti M. J Thorac Oncol. 2012 Feb;7(2):281-90.
4. Brown AF, Sirohi D, Fukuoka J, Cagle P, Policarpio-Nicolas M, Tacha D, Jagirdar J. Arch Pathol Lab Med. 2013 Jan 4.
5. Karni-Schmidt O, Castillo-Martin M, Shen TH, Gladoun N, Domingo-Domenech J, Sanchez-Carbayo M, Li Y, Lowe S, Prives C, Cordon-Cardo C. Am J Pathol. 2011 Mar;178(3):1350-60.
6. Signoretti S, Waltregny D, Dilks J, Isaac B, Lin D, Garraway L, Yang A, Montironi R, McKeon F, Loda M. Am J Pathol. 2000 Dec;157(6):1769-75.
7. Barbareschi M, Pecciarini L, Cangi MG, Macrì E, Rizzo A, Viale G, Doglioni C. Am J Surg Pathol. 2001 Aug;25(8):1054-60.
8. Hibi K, Trink B, Patturajan M, Westra WH, Caballero OL, Hill DE, Ratovitski EA, Jen J, Sidransky D. Proc Natl Acad Sci USA. 2000 May 9;97(10):5462-7.
9. Center for Disease Control Manual. Guide: Safety Management, NO. CDC-22, Atlanta, GA. April 30, 1976 “Decontamination of Laboratory Sink Drains to Remove Azide Salts.”
10. Clinical and Laboratory Standards Institute (CLSI). Protection of Laboratory workers from occupationally Acquired Infections; Approved guideline-Third Edition CLSI document M29-A3 Wayne, PA 2005.