Myeloperoxidase

Product Description

The Myeloperoxidase (P) (R) antibody is a rabbit polyclonal antibody prepared from the purified immunoglobulin fraction of rabbit antiserum. This antibody has been shown to be a specific marker for myeloid cells and is commonly used as part of an immunohistochemical panel for immunophenotyping acute lymphoblastic leukemia in bone marrow biopsies.¹⁵ Myeloperoxidase is readily detectable in myeloblasts and immature myeloid cells associated with various hematopoietic disorders, including acute myelogenous leukemia, progranulocytic leukemia, monomyelocytic leukemia, erythroleukemia, and myeloblastomas.¹⁶

Specifications

1. Toth B, Wehrmann M, Kaiserling E, Horny HP. Immunophenotyping of acute lymphoblastic leukaemia in routinely processed bone marrow biopsy specimens. J Clin Pathol 1999 Sep;52(9):688-92
2. Pinkus GS, Pinkus JL. Myeloperoxidase: a specific marker for myeloid cells in paraffin sections. Mod Pathol 1991 Nov;4(6):733-41.
3. Center for Disease Control Manual. Guide: Safety Management, NO. CDC-22, Atlanta, GA. April 30, 1976 “Decontamination of Laboratory Sink Drains to Remove Azide Salts.”
4. National Committee for Clinical Laboratory Standards (NCCLS). Protection of laboratory workers from infectious diseases transmitted by blood and tissue; proposed guideline. Villanova, PA 1991;7(9). Order code M29-P.