CK5 + p63

Product Description

Cytokeratin 5 is a 58 kDa protein that is closely related to CK6. They share similar tissue distribution and are found in various proportions in many nonkeratinizing stratified squamous epithelia such as tongue mucosa, basal epithelia hair follicles, trachea, as well as basal cells in prostate glands and in mammary glands. CK5 is also expressed in most epithelial and biphasic mesotheliomas. p63 is detected in prostatic basal cells in normal prostate, however, it is negative in malignant tumors of the prostate gland. Thus, p63 is useful as a differential marker for benign and malignant tumors of prostate gland and can be useful as a negative marker. p63 also stains basal cells in mammary glands.^15-17

Specifications

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