CD5

Product Description

CD5 is a T-cell associated marker that is also expressed by two B-cell neoplasms: lymphocytic leukemia and mantle cell lymphoma. CD5 antigen is expressed in 95% of thymocytes and 72% of peripheral blood lymphocytes. In lymph nodes, CD5 is mainly reactive with T-cells.^17-20 It has been shown to react with thymic carcinomas, but rarely in thymomas.^15,16 It has also been observed in a subset of intravascular large B-cell lymphomas and marks some anaplastic large cell lymphomas.^17,18

Specifications

1. Baseggio L, et al. Haematologica. 2010 Apr; 95(4):604-12.
2. Belaud-Rotureau MA, et al. Mod Pathol. 2002 May; 15(5):517-25.
3. Tateyama H, et al. Am J Clin Pathol 1999 Feb; 111(2):235-40.
4. de Leon ED, et al. Mod Pathol 1998 Nov; 11(11):1046-51.
5. Khalidi HS, et al. Mod Pathol 1998 Oct; 11(10):983-8.
6.Kaufmann O, et al. Am J Clin Pathol 1997 Dec; 108(6):669-73.