Product Description
CD3 is expressed throughout the T-cell differentiation process. CD3 is a highly specific and sensitive T-cell lineage marker, making it ideal for the immunohistochemical analysis of lymphohematologic malignancies. Notable exceptions include some of the more aggressive large T-cell lymphomas and CD30 (Ki-1) positive anaplastic large cell lymphomas, which may not express detectable antigen (1-3). A monoclonal antibody to human CD3 is regarded as a reliable pan T-cell antibody used in identifying lymphomas and lymphocytic colitis in paraffin sections (4).