Bcl-6 [LN22]
$252.00 – $1,191.00
Description
Product Description
The Bcl-6 gene, originally cloned from a tumor with 3q27 translocation, is commonly expressed in large cell lymphomas. In humans, Bcl-6 encodes for a Kruppel-type zinc finger protein that is believed to be important in germinal center formation. Bcl-6 protein is expressed mainly by follicle center cells and in a few interfollicular T-lymphocytes. Bcl-6 has also been detected in Burkitt’s lymphoma and in nodular lymphocyte predominant Hodgkin’s disease. Bcl-6 is not expressed in hairy cell leukemia, mantle cell or marginal-zone derived lymphomas. This antibody demonstrates strong nuclear reactivity.
Specifications
Specifications
| Intended Use | |
|---|---|
| Source | |
| Clone | |
| Isotype | |
| Antigen | |
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Datasheets & SDS
| Download Data Sheet |
| Download Q Series Data Sheet |
| Download SDS Sheet |
Browse more documents for this product (IFUs, datasheets, translations, SDS, and more).
References
1. Pillai RK, et al. Am J Surg Pathol. 2013 Mar; 37(3):323-32.
2. Hoefnagel JJ, et al. Br J Dermatol. 2003 Dec; 149(6):1183-91.
3. Dunphy CH, et al. Leuk Lymphoma. 2001 May; 41(5-6):585-92.
4. Dogan A, et al. Am J Surg Pathol. 2000 Jun; 24(6):846-52.
5. Yang B, et al. Am J Surg Pathol. 2000 May; 24(5):694-702.
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