As anyone who has worked in histology will tell you, a successful staining process begins long before the staining protocol itself. In fact, factors that will determine a stain’s success or failure start to come into play soon as the tissue is removed from the patient’s body. As such, proper education and training for all […]

Validation is an essential step for setting up a new laboratory procedure, whether it incorporates immunohistochemical (IHC) or routine ematoxylin and eosin (H&E) staining. The validation process involves repeatedly testing the procedure over a large quantity and range of specimens in order to ensure the procedure will yield consistent and reproducible results. This, in turn, […]

Tissue microarrays (TMAs) are paraffin blocks that include multiple samples from different tissue types meant to provide a comprehensive multiplex staining profile. The sections from TMA blocks can be used for all types of tissue staining techniques, including immunohistochemistry and in situ hybridization.  In order to create a TMA block, cylindrical tissue samples are collected […]

Mohs IHC Staining Procedures: Why the ‘Kit’ Approach May Not Be the Best Mohs surgery is a quick and highly effective procedure designed to treat skin cancer. This surgical procedure can be used to treat basal cell carcinoma, squamous cell carcinoma, and melanoma and has success rates as high as 99 percent.1 During a Mohs […]

Chromogenic multiplexing procedures represent a set of techniques that permit the identification of two or more target antigens that can be microscopically differentiated by cellular location and/or color. Multiplexing has become increasingly popular as pathologists and other scientists have gained an appreciation for the significant clinical and technical benefits that such procedures provide.

Chromogenic multiplexing procedures represent a set of techniques that permit the identification of two or more target antigens that can be microscopically differentiated by cellular location and/or color. Multiplexing has become increasingly popular as pathologists and other scientists have gained an appreciation for the significant clinical and technical benefits that such procedures provide. Creating a […]

Since 1992, Medicare has paid for the services of physicians and other billing professionals under the physician fee schedule (PFS). Physicians’ services paid under the PFS are furnished in a variety of settings, including physician offices, hospitals, ambulatory surgical centers, and clinical laboratories. For many diagnostic tests and a limited number of other services under […]

San Francisco, CA, January 5, 2021 – Biocare Medical, LLC, a leading provider of innovative immunohistochemistry (IHC) instrumentation and reagents, announces the release of the fully automated staining platform ONCORE Pro™ for IHC and ISH applications. The in vitro diagnostic (IVD) labeled ONCORE Pro Automated Slide Staining System is a compact powerhouse for any clinical […]