p63
p53 homologue p63 encodes for different isotypes able to either transactivate p53 reporter genes (TAp63) or act as p53-dominant-negatives. p63 is detected in prostate basal cells in normal prostate, however, it is negative in malignant tumors of the prostate gland. Thus p63 is useful as a differential marker for benign and malignant tumors of prostate gland and can be used in a panel of antibodies such as HMW CK (34ßE12), PSA and PSAP. p63 may play a significant role in prostate development by maintaining a prostate stem cell population. Striated muscle staining may be observed with p63.
| Ordering Information |
Catalog Number |
Volume |
| Concentrate |
CM 163 |
A, B, C, H, JJ |
| Predilute |
PM 163 |
AA, H |
| intelliPATH™ |
IP 163 |
G10 |
| VP Echelon |
VP 163 |
G, G25 |
| A / AK = 0.1 ml |
B / BK = 0.5 ml |
C / CK = 1.0 ml |
G5 = 5.0 ml |
AA = 6.0 ml |
H / G25 = 25 ml |
L = 100 ml |
