Gross Cystic Disease Fluid Protein-15

Breast cancer stained with GCDFP-15 (DAB) + Mammaglobin (FR)

Glycoproteins, including GCDFP-15. It is considered to be a marker of apocrine differentiation. Numerous studies have shown GCDFP-15 (BRST-2) to be a specific marker for breast cancer in formalin-fixed paraffin-embedded tissues and in cytologic preparation (fine needle aspirates). Studies on breast cancer have shown, with respect to specificity and sensitivity, an overall rating of 95% and 74% respectively. Another study was conducted on fine needle aspirates and statistics showed that 56.5% of primary and recurrent or metastatic breast carcinomas were expressed with GCDFP-15. Other types of tissues that express GCDFP-15 are axillary sweat glands and submandibular salivary glands.

Specifications  
Intended Use
Source
Species Reactivity ,
Clone
Isotype
Antigen
Cellular Localization
Positive Control
Normal Tissue
Abnormal Tissue
Ordering Information Catalog Number Volume
Concentrate CM 113 A, B
Predilute PM 113 AA
intelliPATH™ IP 113 G10
VP Echelon Use Predilute
A / AK = 0.1 ml B / BK = 0.5 ml C / CK = 1.0 ml G5 = 5.0 ml AA = 6.0 ml H / G25 = 25 ml L = 100 ml