BAC to Basics: The Science of BAC Libraries

Fluorescence In Situ Hybridization (FISH) is a powerful technique used to visualize specific sequences within chromosomes or genomes. It involves the use of fluorescently labeled probes that bind to complementary target sequences, allowing researchers to identify and locate specific genes or regions of interest. Bacterial artificial chromosome (BAC) libraries play a crucial role in the development of fluorescence in situ hybridization (FISH) probes.