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The XM Factor is a potent blocker for eliminating endogenous mouse IgG in mouse tissues. It has been specially designed to work with BIOCARE’s Rabbit on Rodent and Goat Polymer detection systems. XM Factor cannot be used with Mouse on Mouse AP or HRP polymer. By adding XM Factor to the polymer detection, endogenous mouse IgG is dramatically reduced and/or is completely eliminated. BIOCARE has also developed Rodent Block M that blocks for nonspecific background staining, and at the same time, also helps reduce endogenous mouse IgG. The combination of Rodent Block M and the XM Factor provide clean staining for mouse on mouse protocols. It can also be used on an automated staining system.