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The pH of retrieval solution at high temperature can be critical for proper immunohistochemical (IHC) staining.
Solutions change pH as the temperature rises. The pH of tris-based retrieval solutions lowers as the temperature
rises. To assure quality control and consistent IHC staining, BIOCARE has developed heat-tested pH strips that
give accurate and the true pH at high temperatures. The pH of a solution should be recorded at the temperature
used. The laboratory investigator can now record pH on a daily basis, and comply with CAP and JCOH inspection.