Cytokeratin LMW (8/18)

Breast cancer stained with Low Molecular Weight Cytokeratin antibody

Clone 5D3 recognizes cytokeratin (CK) 8 and 18 intermediate filament proteins. These are 52.5 kD and 45kD respectively. In normal tissues, 5D3 recognizes all simple and glandular epithelium. In neoplastic tissues, 5D3 may prove useful for the identification of adenocarcinomas and some squamous cell carcinomas. Use in conjunction with HMW CK to rule out squamous cell carcinoma. Keratinizing squamous carcinomas are generally negative. It works well in formalin-fixed, paraffinembedded tissue sections.

Specifications  
Intended Use
Source
Species Reactivity ,
Clone
Isotype
Antigen
Cellular Localization
Positive Control
Normal Tissue
Abnormal Tissue ,
Ordering Information Catalog Number Volume
Concentrate CM 056 A, C
Predilute PM 056 AA, H
intelliPATH™ IP 056 G10, G20
VP Echelon N/A N/A
A / AK = 0.1 ml B / BK = 0.5 ml C / CK = 1.0 ml G5 = 5.0 ml AA = 6.0 ml H / G25 = 25 ml L = 100 ml