Cytokeratin LMW (8/18)

Product Description

Clone 5D3 recognizes cytokeratin (CK) 8 and 18 intermediate filament proteins. These are 52.5 kDa and 45 kDa respectively. In normal tissues, 5D3 recognizes all simple and glandular epithelium.^15-16 In neoplastic tissues, 5D3 may prove useful for the identification of adenocarcinomas and some squamous cell carcinomas.¹⁵ Use in conjunction with HMW CK to rule out squamous cell carcinoma. Keratinizing squamous carcinomas are generally negative. It works well in formalin-fixed, paraffin-embedded tissue sections.¹⁶

Specifications

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