Bcl-6 [LN22]
The Bcl-6 gene, originally cloned from a tumor with 3q27 translocation, is commonly expressed in large cell lymphomas. In humans, Bcl-6 encodes for a Kruppel-type zinc finger protein that is believed to be important in germinal center formation. Bcl-6 is expressed mainly by follicle center cells and in a few interfollicular Tlymphocytes. Bcl-6 has also been detected in Burkitt’s lymphoma and in nodular lymphocyte predominant Hodgkin’s disease. Bcl-6 is not expressed in hairy cell leukemia, mantle cell or marginal-zone derived lymphomas. This antibody demonstrates strong nuclear reactivity.
| Ordering Information |
Catalog Number |
Volume |
| Concentrate |
CM 410 |
A, C |
| Predilute |
PM 410 |
AA |
| intelliPATH™ |
IP 410 |
G10 |
| VP Echelon |
N/A |
N/A |
| A / AK = 0.1 ml |
B / BK = 0.5 ml |
C / CK = 1.0 ml |
G5 = 5.0 ml |
AA = 6.0 ml |
H / G25 = 25 ml |
L = 100 ml |
