MLL Break Apart Orange/Green

Product Description

Infant acute leukemia, including AML and ALL, have been reported to have incidences of MLL rearrangements in 60-80% of cases (1). It has been demonstrated that one of the most effective ways of identifying these rearrangements is with a MLL break apart probe (2).

Specifications

1. Frequency and prognostic significance of HRX rearrangements in infant acute lymphoblastic leukemia; a Pediatric Oncology Group study. Rubnitz, J.E,Link, M.P,Shuster, J.J, et al. Blood 1994; 84:570-573
2. Hematologic Malignancies: Acute Leukemias. Ed: Faderl, S.H. and Kantarjian, H.M. Springer Scientific Press, Nov 2007
3. Clinical and Laboratory Standards Institute (CLSI). Protection of Laboratory workers from occupationally Acquired Infections; Approved Guideline-Fourth Edition CLSI document M29-A4 Wayne, PA 2014.