Cytokeratin 5

Product Description

CK5 is a 58 kDa protein that is closely related to CK6.15 ELISA was carried out to screen for antibodies that were positive for CK5 and negative with CK6. Results showed that the XM26 clone was positive for CK5 protein and was negative for the CK6 protein. CK5 tissue distribution is in many nonkeratinizing stratified squamous epithelia such as tongue mucosa, basal epithelia hair follicles, trachea, as well as basal cells in prostate glands and myoepithelial cells in mammary glands. CK5 is also expressed in most epithelial and biphasic mesotheliomas.¹⁶ CK5 has also been noted in large cell carcinomas and pulmonary squamous cell carcinomas.^15,16

Specifications

1. Bocker W, et al. Lab Invest. 2002 Jun; 82(6):737-46.
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3. Bhargava R, et al. Am J Clin Pathol. 2008 Nov; 130(5):724-30.
4. Brunnstrom H, et al. Am J Clin Pathol. 2013 Jul; 140(1):37-46.