Cytokeratin 7 (CK7)
$250.00 – $954.00
Description
Product Description
Cytokeratin 7 is an intermediate filament protein (IFP) of 54 kDa that recognizes the simple epithelium found in most glandular and transitional epithelia; but not that which is found in stratified squamous epithelia. This monoclonal antibody [OV-TL 12/30] is highly specific to cytokeratin 7 and shows no cross-reaction with other IFPs. Cytokeratin 7 is a basic cytokeratin, and is expressed in epithelial cells of ovary, lung, and breast, but not of colon or gastrointestinal tract. It is often used in conjunction with cytokeratin 20 in distinguishing ovarian, pulmonary, and breast carcinomas (CK7+) from colon carcinomas (CK7-).15-20
Specifications
Specifications
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References
1. Tot T. Eur J Cancer. 2002 Apr; 38(6):758-63.
2. Lagendijk JH, et al. Hum Pathol. 1998 May; 29(5):491-7.
3. Tan J, et al. Hum Pathol. 1998 Apr; 29(4):390-6.
4. Bouwens L. J Pathol. 1998 Mar; 184(3):234-9.
5. Loy TS, Calaluce RD, Keeney GL. Mod Pathol. 1996 Nov; 9(11):1040-4.
6. Wauters CC, et al. Hum Pathol. 1995 Aug; 26(8):852-5.
7. Loy TS, Calaluce RD. Am J Clin Pathol. 1994 Dec; 102(6):764-7.
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