IGH (14q32) Green/ BCL2 (18q21) Orange

Product Description

Follicular lymphoma (FL) has a characteristic chromosomal translocation involving the t(14;18)(q32;q21) loci. This results in the BCL2 oncogene getting transposed into the IGH gene on the heavy chain1.

The resulting over-expression of BCL2 is strongly associated with the pathogenesis of FL2.

Specifications