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Estrogen Receptor (ER) [6F11 + SP1]
Price range: $1,160.00 through $3,500.00
Description
Product Description
Estrogen Receptor ER antibody clone 6F11 is a 66-kDa protein that mediates the actions of estrogens in estrogen-responsive tissues. The ER gene consists of more than 140kb of genomic DNA divided into 8 exons. These translate into a protein with six functionally discrete domains, labeled A through F. This mouse monoclonal antibody has been established to work in formalin-fixed, paraffin-embedded tissues and has been published in breast cancer studies. The 6F11 clone has been shown to be superior to the 1D5 (Bevitt DJ et al.).
Specifications
Specifications
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Datasheets & SDS
| Download ASR Data Sheet |
| Download SDS Sheet |
Browse more documents for this product (IFUs, datasheets, translations, SDS, and more).
OUS ONLY IVD
| Download OUS Datasheet |
Legal NoticeIVD is NOT for Sale in the United States but may be available in certain countries outside of the United States, please contact your local distributor for more information. |
References
1. Cheang MC et al. (2006) Immunohistochemical Detection Using the New Rabbit Monoclonal Antibody SP1 of Estrogen Receptor in Breast Cancer Is Superior to Mouse Monoclonal Antibody 1D5 in Predicting Survival. J Clin Oncol. [Epub ahead of print].
2. Kaplan PA et al. (2005) An immunohistochemical comparison of two monoclonal antibodies for the evaluation of estrogen receptor status in primary breast carcinoma. Am J Clin Pathol.123(2):276-80
3. Bevitt DJ et al. (1977) New monoclonal antibodies to oestrogen and progesterone receptors effective for paraffin section immunohistochemistry. J Pathol Oct; 183 (2):228-32.
4. Center for Disease Control Manual. Guide: Safety Management, NO. CDC-22, Atlanta, GA. April 30, 1976 “Decontamination of Laboratory Sink Drains to Remove Azide Salts.”
5. National Committee for Clinical Laboratory Standards (NCCLS). Protection of laboratory workers from infectious diseases transmitted by blood and tissue; proposed guideline. Villanova, PA 1991; 7(9). Order code M29-P.
