Oct-2
Oct-2 is a transcription factor belonging to the POU homeo-domain family that binds to the immunoglobin (Ig) gene octamer sites regulating B-cell specific genes. Oct-2 protein expression is seen in germinal center B-cells and is significantly greater in germinal center derived B-cell lymphomas. Routine morphologic and immunohistochemical studies can distinguish most cases of classic Hodgkin’s lymphoma (CHL) from its imitators; however, the differences in expression of BSAP, OCT-2, BOB.1 and the pan B-cell markers CD20, CD22, and CD79a may aid in distinguishing difficult cases of CHL from nodular lymphocyte predominant Hodgkin’s lymphoma and diffuse large B-cell lymphomas.
| Ordering Information |
Catalog Number |
Volume |
| Concentrate |
CM 417 |
A, B |
| Predilute |
PM 417 |
AA |
| intelliPATH™ |
N/A |
N/A |
| VP Echelon |
N/A |
N/A |
| A / AK = 0.1 ml |
B / BK = 0.5 ml |
C / CK = 1.0 ml |
G5 = 5.0 ml |
AA = 6.0 ml |
H / G25 = 25 ml |
L = 100 ml |
