Cyclin D1

Mantle cell lymphoma stained with Cyclin D1 antibody

This rabbit monoclonal antibody recognizes a protein of 36 kDa, identified as Cyclin D1 (also known as Bcl-1 or PRAD-1). Cyclin D1 is a regulatory subunit of certain protein kinases thought to advance the G1 phase of the cell cycle. Cyclin D1 used in tandem with CD5, CD10 and CD23 is the most reliable immunohistochemical marker for the mantle cell lymphoma. Cyclin D1 is also expressed in invasive breast cancer. Due to the superior technology in the development of this antibody, its binding capacity is superior to mouse monoclonal antibodies and is virtually background free.

Specifications  
Intended Use
Source
Species Reactivity ,
Clone
Isotype
Antigen
Cellular Localization
Positive Control ,
Normal Tissue
Abnormal Tissue ,
Ordering Information Catalog Number Volume
Concentrate CME 432 A, C
Predilute PME 432 AA
intelliPATH™ N/A N/A
VP Echelon N/A N/A
A / AK = 0.1 ml B / BK = 0.5 ml C / CK = 1.0 ml G5 = 5.0 ml AA = 6.0 ml H / G25 = 25 ml L = 100 ml
Data Sheets
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