CD31
CD31 (PECAM-1) is a glycoprotein expressed on endothelial cells and in platelets. It is known to be involved in cell signaling and cell adhesion. PECAM-1 mediates cell to cell adhesion and supports the idea that it may be involved in some of the interactive events taking place during thrombosis, wound healing, and angiogenesis. CD31 is of value in the study of benign and malignant vascular tumors. Staining for CD31 has also been used to measure angiogenesis, which reportedly predicts tumor recurrence. Reliable identification of endothelial cells is a prerequisite for understanding vascularity changes in many cardiovascular diseases and therapeutic interventions. This rat anti-mouse CD31 antibody is expressed in endothelial cells from a variety of mouse tissues and is weakly expressed in peripheral lymphoid cells and platelets. CD31 is well suited for formalin-fixed paraffin-embedded tissues.
| Ordering Information |
Catalog Number |
Volume |
| Concentrate |
CM 303 |
A, B |
| Predilute |
N/A |
N/A |
| intelliPATH™ |
N/A |
N/A |
| VP Echelon |
N/A |
N/A |
| A / AK = 0.1 ml |
B / BK = 0.5 ml |
C / CK = 1.0 ml |
G5 = 5.0 ml |
AA = 6.0 ml |
H / G25 = 25 ml |
L = 100 ml |
